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Entries: 1-10  
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Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance
Authors: Klüter, Sabine; Simard, Jeffrey R.; Rode, Haridas B.; Grütter, Christian; Pawar, Vijaykumar; Raaijmakers, Hans C A.; Barf, Tjeerd A.; Rabiller, Matthias; van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010-12-10
Title of Journal: ChemBioChem
Volume: 11
Issue / Number: 18
Start Page: 2557
End Page: 2566
Sequence Number of Article: 1
Document Type: Article
ID: 525509.0
Strukturbasierte Entwicklung von Assaysystemen und Charakterisierung von orthosterischen und allosterischen Kinaseinhibitoren
Authors: Klüter, Sabine
Name of University: Technische Universität Dortmund
Place of University: Dortmund
Date of Approval (YYYY-MM-DD): 2010-08-26
Document Type: PhD-Thesis
ID: 576593.0
Displacement Assay for the Detection of Stabilizers of Inactive Kinase Conformations
Authors: Klüter, Sabine; Grütter, Christian; Naqvi, Tabassum; Rabiller, Matthias; Simard, Jeffrey R.; Pawar, Vijaykumar; Getlik, Matthäus; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010-01-14
Title of Journal: Journal of Medicinal Chemistry
Volume: 53
Issue / Number: 1
Start Page: 357
End Page: 367
Sequence Number of Article: 1
Document Type: Article
ID: 443578.0
Chemogenomic profiling provides insights into the limited activity of irreversible EGFR inhibitors in tumor cells expressing the T790M EGFR resistance mutation
Authors: Sos, Martin L.; Rode, Haridas B.; Heynck, Stefanie; Peifer, Martin; Fischer, Florian; Klüter, Sabine; Pawar, Vijakumar G.; Reuter, Cecile; Heuckmann, Johannes M.; Weiss, Jonathan; Ruddigkeit, Lars; Rabiller, Matthias; Koker, Mirjam; Simard, Jeffrey R.; Getlik, Matthäus; Yuza, Yuki; Chen, Tzu-Hsiu; Greulich, Heidi; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Cancer Research
Volume: 70
Issue / Number: 3
Start Page: 868
End Page: 874
Document Type: Article
ID: 472769.0
Proteus in the World of Proteins: Conformational Changes in Protein Kinases
Authors: Rabiller, Matthias; Getlik, Matthäus; Klüter, Sabine; Richters, André; Tückmantel, Sandra; Simard, Jeffrey R.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Archiv der Pharmazie
Volume: 343
Issue / Number: 4
Start Page: 193
End Page: 206
Sequence Number of Article: 1
Document Type: Article
ID: 476390.0
Chemogenomic Profiling Provides Insights into the Limited Activity of Irreversible EGFR Inhibitors in Tumor Cells Expressing the T790M EGFR Resistance Mutation
Authors: Sos, Martin L; Rode, Haridas B.; Heynck, Stefanie; Peifer, Martin; Fischer, Florian; Klüter, Sabine; Pawar, Vijaykumar G.; Reuter, Cecile; Heuckmann, Johannes M.; Weiss, Jonathan; Ruddigkeit, Lars; Rabiller, Matthias; Koker, Mirjam; Simard, Jeffrey R.; Getlik, Matthäus; Yuza, Yuki; Chen, Tzu-Hsiu; Greulich, Heidi; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Cancer Research
Volume: 70
Issue / Number: 3
Start Page: 868
End Page: 874
Sequence Number of Article: 1
Document Type: Article
ID: 478045.0
Hybrid Compound Design to Overcome the Gatekeeper T338M Mutation in cSrc
Authors: Getlik, Matthäus; Grütter, Christian; Simard, Jeffrey R.; Klüter, Sabine; Rabiller, Matthias; Rode, Haridas B.; Robubi, Armin; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2009-05-22
Title of Journal: Journal of Medicinal Chemistry
Volume: 52
Issue / Number: 13
Start Page: 3915
End Page: 3926
Sequence Number of Article: 1
Document Type: Article
ID: 433833.0
A new screening assay for allosteric inhibitors of cSrc
Authors: Simard, Jeffrey R.; Klüter, Sabine; Grütter, Christian; Getlik, Matthäus; Rabiller, Matthias; Rode, Haridas B.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2009-04-26
Title of Journal: Nature Chemical Biology
Volume: 5
Issue / Number: 6
Start Page: 394
End Page: 396
Sequence Number of Article: 1
Document Type: Article
ID: 430802.0
High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38α
Authors: Simard, Jeffrey R.; Grütter, Christian; Pawar, Vijaykumar; Aust, Beate; Wolf, Alexander; Rabiller, Matthias; Wulfert, Sabine; Robubi, Armin; Klüter, Sabine; Ottmann, Christian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2009
Title of Journal: Journal of American Chemical Society
Volume: 131
Issue / Number: 51
Start Page: 18478
End Page: 18488
Sequence Number of Article: 1
Document Type: Article
ID: 446597.0
Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR
Authors: Michalczyk, Anja; Klüter, Sabine; Rode, Haridas B.; Simard, Jeffrey R.; Grütter, Christian; Rabiller, Matthias; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2008
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 16
Issue / Number: 7
Start Page: 3482
End Page: 3488
Sequence Number of Article: 1
Document Type: Article
ID: 475909.0
Entries: 1-10  
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