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Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
Authors: Gusev, Alexander; Lee, S. Hong; Trynka, Gosia; Finucane, Hilary; Vilhjálmsson, Bjarni J.; Xu, Han; Zang, Chongzhi; Ripke, Stephan; Bulik-Sullivan, Brendan; Stahl, Eli; Schizophrenia Working Group of the Psychiatric Genomics Consortium; SWE-SCZ Consortium; Kähler, Anna K.; Hultman, Christina M.; Purcell, Shaun M.; McCarroll, Steven A.; Daly, Marc; Pasaniuc, Bogdan; Sullivan, Patrick F.; Neale, Benjamin M.; Wray, Naomi R.; Raychaudhuri, Soumya; Price, Alkes L.; Corvin, A.; Walters, J. T.; Farh, K. H.; Holmans, P. A.; Lee, P.; Collier, D. A.; Huang, H.; Pers, T. H.; Agartz, I.; Agerbo, E.; Albus, M.; Alexander, M.; Amin, F.; Bacanu, S. A.; Begemann, Martin; Belliveau, R. A.; Bene, J.; Bergen, S. E.; Bevilacqua, E.; Bigdeli, T. B.; Black, D. W.; Børglum, A. D.; Bruggeman, R.; Buccola, N. G.; Buckner, R. L.; Byerley, W.; Cahn, W.; Cai, G.; Campion, D.; Cantor, R. M.; Carr, V. J.; Carrera, N.; Catts, S. V.; Chambert, K. D.; Chan, R. C.; Chen, R. Y.; Chen, E. Y.; Cheng, W.; Cheung, E. F.; Chong, S. A.; Cloninger, C. R.; Cohen, D.; Cohen, N.; Cormican, P.; Craddock, N.; Crowley, J. J.; Curtis, D.; Davidson, M.; Davis, K. L.; Degenhardt, F.; Del Favero, J.; DeLisi, L. E.; Demontis, D.; Dikeos, D.; Dinan, T.; Djurovic, S.; Donohoe, G.; Drapeau, E.; Duan, J.; Dudbridge, F.; Durmishi, N.; Eichhammer, P.; Eriksson, J.; Escott-Price, V.; Essioux, L.; Fanous, A. H.; Farrell, M. S.; Frank, J.; Franke, L.; Freedman, R.; Freimer, N. B.; Friedl, M.; Friedman, J. I.; Fromer, M.; Genovese, G.; Georgieva, L.; Gershon, E. S.; Giegling, I.; Giusti-Rodriguez, P.; Godard, S.; Goldstein, J. I.; Golimbet, V.; Gopal, S.; Gratten, J.; Grove, J.; de Haan, L.; Hammer, Christian; Hamshere, M. L.; Hansen, M.; Hansen, T.; Haroutunian, V.; Hartmann, A. M.; Henskens, F. A.; Herms, S.; Hirschhorn, J. N.; Hoffmann, P.; Hofman, A.; Hollegaard, M. V.; Hougaard, D. M.; Ikeda, M.; Joa, I.; Julià, A.; Kahn, R. S.; Kalaydjieva, L.; Karachanak-Yankova, S.; Karjalainen, J.; Kavanagh, D.; Keller, M. C.; Kelly, B. J.; Kennedy, J. L.; Khrunin, A.; Kim, Y.; Klovins, J.; Knowles, J. A.; Konte, B.; Kucinskas, V.; Kucinskiene, Z. A.; Kuzelova-Ptackova, H.; Laurent, C.; Keong, J. L.; Legge, S. E.; Lerer, B.; Li, M.; Li, T.; Liang, K. Y.; Lieberman, J.; Limborska, S.; Loughland, C. M.; Lubinski, J.; Lnnqvist, J.; Macek, M.; Magnusson, P. K.; Maher, B. S.; Maier, W.; Mallet, J.; Marsal, S.; Mattheisen, M.; Mattingsdal, M.; McCarley, R. W.; McDonald, C.; McIntosh, A. M.; Meier, S.; Meijer, C. J.; Melegh, B.; Melle, I.; Mesholam-Gately, R. I.; Metspalu, A.; Michie, P. T.; Milani, L.; Milanova, V.; Mokrab, Y.; Morris, D. W.; Mors, O.; Mortensen, P. B.; Murphy, K. C.; Murray, R. M.; Myin-Germeys, I.; Mller-Myshok, B.; Nelis, M.; Nenadic, I.; Nertney, D. A.; Nestadt, G.; Nicodemus, K. K.; Nikitina-Zake, L.; Nisenbaum, L.; Nordin, A.; O'Callaghan, E.; O'Dushlaine, C.; O'Neill, F. A.; Oh, S. Y.; Olincy, A.; Olsen, L.; van Os, J.; Pantelis, C.; Papadimitriou, G. N.; Papiol, Sergi; Parkhomenko, E.; Pato, M. T.; Paunio, T.; Pejovic-Milovancevic, M.; Perkins, D. O.; Pietilinen, O.; Pimm, J.; Pocklington, A. J.; Powell, J.; Price, A.; Pulver, A. E.; Quested, D.; Rasmussen, H. B.; Reichenberg, A.; Reimers, M. A.; Richards, A. L.; Roffman, J. L.; Roussos, P.; Ruderfer, D. M.; Salomaa, V.; Sanders, A. R.; Schall, U.; Schubert, C. R.; Schulze, T. G.; Schwab, S. G.; Scolnick, E. M.; Scott, R. J.; Seidman, L. J.; Shi, J.; Sigurdsson, E.; Silagadze, T.; Silverman, J. M.; Sim, K.; Slominsky, P.; Smoller, J. W.; So, H. C.; Spencer, C. C.; Stahl, E. A.; Stefansson, H.; Steinberg, S.; Stogmann, E.; Straub, R. E.; Strengman, E.; Strohmaier, J.; Stroup, T. S.; Subramaniam, M.; Suvisaari, J.; Svrakic, D. M.; Szatkiewicz, J. P.; Sderman, E.; Thirumalai, S.; Toncheva, D.; Tooney, P. A.; Tosato, S.; Veijola, J.; Waddington, J.; Walsh, D.; Wang, Q.; Webb, B. T.; Weiser, M.; Wildenauer, D. B.; Williams, N. M.; Williams, S.; Witt, S. H.; Wolen, A. R.; Wong, E. H.; Wormley, B. K.; Wu, J. Q.; Xi, H. S.; Zai, C. C.; Zheng, X.; Zimprich, F.; Wray, N. R.; Stefansson, K.; Visscher, P. M.; Adolfsson, R.; Andreassen, O. A.; Blackwood, D. H.; Bramon, E.; Buxbaum, J. D.; Brglum, A. D.; Cichon, S.; Darvasi, A.; Domenici, E.; Ehrenreich, Hannelore; Esko, T.; Gejman, P. V.; Gill, M.; Gurling, H.; Iwata, N.; Jablensky, A. V.; Jönsson, E. G.; Kendler, K. S.; Kirov, G.; Knight, J.; Lencz, T.; Levinson, D. F.; Li, Q. S.; Liu, J.; Malhotra, A. K.; McQuillin, A.; Mortensen, P. B.; Mowry, B. J.; Nthen, M. M.; Ophoff, R. A.; Owen, M. J.; Palotie, A.; Pato, C. N.; Petryshen, T. L.; Posthuma, D.; Rietschel, M.; Riley, B. P.; Rujescu, D.; Sham, P. C.; Sklar, P.; St. Clair, D.; Weinberger, D. R.; Wendland, J. R.; Werge, T.; Daly, M. J.; O'Donovan, M. C.; O'Dushlaine, C.; Chambert, K.; Moran, J. L.; Akterin, S.; Bergen, S.; Magnusson, P. K.; Neale, B. M.; Ruderfer, D.; Scolnick, E.; Purcell, S.; McCarroll, S.
Date of Publication (YYYY-MM-DD): 2014-11-06
Title of Journal: American Journal of Human Genetics
Volume: 95
Issue / Number: 5
Start Page: 535
End Page: 552
Document Type: Article
ID: 696041.0
 
Full text / Content available
Biological insights from 108 schizophrenia-associated genetic loci
Advisors: Kähler, Anna K.
Editors: Psychosis Endophenotypes International Consortium; Wellcome Trust Case-control Consortium
Authors: Ripke, Stephan; Neale, Benjamin M.; Corvin, Aiden; Walters, James T. R.; Farh, Kai-How; Holmans, Peter A.; Lee, Phil; Bulik-Sullivan, Brendan; Collier, David A.; Huang, Hailiang; Pers, Tune H.; Agartz, Ingrid; Agerbo, Esben; Albus, Margot; Alexander, Madeline; Amin, Farooq; Bacanu, Silvius A.; Begemann, Martin; Belliveau, Richard A.; Bene, Judit; Bergen, Sarah E.; Bevilacqua, Elizabeth; Bigdeli, Tim B.; Black, Donald W.; Bruggeman, Richard; Buccola, Nancy G.; Buckner, Randy L.; Byerley, William; Cahn, Wiepke; Cai, Guiqing; Campion, Dominique; Cantor, Rita M.; Carr, Vaughan J.; Carrera, Noa; Catts, Stanley V.; Chambert, Kimberly D.; Chan, Raymond C. K.; Chen, Donald Y. L.; Chen, Eric Y. H.; Cheng, Wei; Cheung, Eric F. C.; Chong, Siow Ann; Cloninger, C. Robert; Cohen, David; Cohen, Nadine; Cormican, Paul; Craddock, Nick; Crowley, James J.; Curtis, David; Davidson, Michael; Davis, Kenneth L.; Degenhardt, Franziska; Del Favero, Jurgen; Demontis, Ditte; Dikeos, Dimitris; Dinan, Timothy; Djurovic, Srdjan; Donohoe, Gary; Drapeau, Elodie; Duan, Jubao; Dudbridge, Frank; Durmishi, Naser; Eichhammer, Peter; Eriksson, Johan; Escott-Price, Valentina; Essioux, Laurent; Fanous, Ayman H.; Farrell, Martilias S.; Frank, Josef; Franke, Lude; Freedman, Robert; Freimer, Nelson B.; Friedl, Marion; Friedman, Joseph I.; Fromer, Menachem; Genovese, Giulio; Georgieva, Lyudmila; Giegling, Ina; Giusti-Rodriguez, Paola; Godard, Stephanie; Goldstein, Jacqueline I.; Golimbet, Vera; Gopal, Srihari; Gratten, Jacob; de Haan, Lieuwe; Hammer, Christian; Hamshere, Marian L.; Hansen, Mark; Hansen, Thomas; Haroutunian, Vahram; Hartmann, Annette M.; Henskens, Frans A.; Herms, Stefan; Hirschhorn, Joel N.; Hoffmann, Per; Hofman, Andrea; Hollegaard, Mads V.; Hougaard, David M.; Ikeda, Masashi; Joa, Inge; Julià, Antonio; Kahn, René S.; Kalaydjieva, Luba; Karachanak-Yankova, Sena; Karjalainen, Juha; Kavanagh, David; Keller, Matthew C.; Kennedy, James L.; Khrunin, Andrey; Kim, Yunjung; Klovins, Janis; Knowles, James A.; Konte, Bettina; Kucinskas, Vaidutis; Kucinskiene, Zita Ausrele; Kuzelova-Ptackova, Hana; Laurent, Claudine; Lee Chee Keong, Jimmy; Lee, S. Hong; Legge, Sophie E.; Lerer, Bernard; Li, Miaoxin; Li, Tao; Liang, Kung-Yee; Lieberman, Jeffrey; Limborska, Svetlana; Loughland, Carmel M.; Lubinski, Jan; Lönnqvist, Jouko; Macek, Milan; Magnusson, Patrik K. E.; Maher, Brion S.; Maier, Wolfgang; Mallet, Jacques; Marsal, Sara; Mattheisen, Manuel; Mattingsdai, Morten; McCarley, Robert W.; McDonald, Colm; McIntosh, Andrew M.; Meier, Sandra; Meijer, Carin J.; Melegh, Bela; Melle, Ingrid; Mesholam-Gately, Raquelle I.; Metspalu, Andres; Michie, Patricia T.; Milani, Lili; Milanova, Vihra; Mokrab, Younes; Morris, Derek W.; Mors, Ole; Murphy, Kieran C.; Murray, Robin M.; Myin-Germeys, Inez; Müller-Myhsok, Bertram; Nelis, Mari; Nenadic, Igor; Nertney, Deborah A.; Nestadt, Gerald; Nicodemus, Kristin K.; Nikitina-Zake, Liene; Nisenbaum, Laura; Nordin, Annelie; O'Callaghan, Eadbhard; O'Dushlaine, Colm; O'Neill, F. Anthony; Oh, Sang-Yun; Olincy, Ann; Olsen, Line; Os, Jim Van; Pantelis, Christos; Papadimitriou, George N.; Papiol, Sergi; Parkhomenko, Elena; Pato, Michele T.; Paunio, Tiina; Pejovic-Milovancevic, Milica; Perkins, Diana O.; Pietiläinen, Olli; Pimm, Jonathan; Pocklington, Andrew J.; Powell, John; Price, Alkes; Pulver, Ann E.; Purcell, Shaun M.; Quested, Digby; Rasmussen, Henrik B.; Reichenberg, Abraham; Reimers, Mark A.; Richards, Alexander L.; Roffman, Joshua L.; Roussos, Panos; Ruderfer, Douglas M.; Salomaa, Veikko; Sanders, Alan R.; Schall, Ulrich; Schubert, Christian R.; Schulze, Thomas G.; Schwab, Sibylle G.; Scolnick, Edward M.; Scott, Rodney J.; Seidman, Larry J.; Shi, Jianxin; Sigurdsson, Engilbert; Silagadze, Teimuraz; Silberman, Jeremy M.; Sim, Kang; Slominsky, Petr; Smoller, Jordan W.; So, Hon-Cheong; Spencer, Chris C. A.; Stahl, Eli A.; Stefansson, Hreinn; Steinberg, Stacy; Stogmann, Elisabeth; Straub, Richard E.; Strengman, Eric; Strohmaier, Jana; Stroup, T. Scott; Subramaniam, Mythily; Suvisaari, Jaana; Svrakic, Dragan M.; Szatkiewicz, Jin P.; Söderman, Erik; Thirumalai, Srinivas; Toncheva, Draga; Tosato, Sarah; Veijola, Juha; Waddington, John; Walsh, Dermot; Wang, Dai; Wang, Qiang; Webb, Bradley T.; Weiser, Mark; Wildenauer, Dieter B.; Williams, Nigel M.; Williams, Stephanie; Witt, Stephanie H.; Wolen, Aaron R.; Wong, Emily H. M.; Wormley, Brandon K.; Xi, Hualin Simon; Zai, Clement C.; Zheng, Xuebin; Zimprich, Fritz; Wray, Naomi R.; Stefansson, Kari; Visscher, Peter M.; Adolfsson, Rolf; Andreassen, Ole A.; Blackwood, Douglas H. R.; Bramon, Elvira; Buxbaum, Joseph D.; Børglum, Anders D.; Cichon, Sven; Darvasi, Ariel; Domenici, Enrico; Ehrenreich, Hannelore; Esko, Tõnu; Gejman, Pablo V.; Gill, Michael; Gurling, Hugh; Hultman, Christina M.; Iwata, Nakao; Jablensky, Assen V.; Jönsson, Erik G.; Kendler, Kenneth S.; Kirov, George; Knight, Jo; Lencz, Todd; Levinson, Douglas F.; Li, Qingqin S.; Liu, Jianjun; Malhotra, Anil K.; McCarroll, Steven A.; McQuillin, Andrew; Moran, Jennifer L.; Mortensen, Preben B.; Mowry, Bryan J.; Nöthen, Markus M.; Ophoff, Roel A.; Owen, Michael J.; Palotie, Aarno; Pato, Carlos N.; Petryshen, Tracy L.; Posthuma, Danielle; Rietschel, Marcella; Riley, Brien P.; Rujescu, Dan; Sham, Pak C.; Sklar, Pamela; St. Clair, David; Weinberger, Daniel R.; Wendland, Jens R.; Werge, Thomas; Daly, Mark J.; Sullivan, Patrick F.; O'Donovan, Michael C.
Date of Publication (YYYY-MM-DD): 2014-07-24
Title of Journal: Nature
Volume: 511
Issue / Number: 7510
Start Page: 421
End Page: 427
Document Type: Article
ID: 695771.0
 
Full text / Content available
Entries: 1-2  
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