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Entries: 1-10  
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Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design
Authors: Richters, André; Ketzer, Julia; Getlik, Matthäus; Grütter, Christian; Schneider, Ralf; Heuckmann, Johannes M.; Heynck, Stefanie; Sos, Martin L.; Gupta, Anu; Unger, Anke; Schultz-Fademrecht, Carsten; Thomas, Roman K.; Bauer, Sebastian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-07-25
Title of Journal: Journal of Medicinal Chemistry
Volume: 56
Issue / Number: 14
Start Page: 5757
End Page: 5772
Sequence Number of Article: 1
Document Type: Article
ID: 669113.0
A framework for identification of actionable cancer genome dependencies in small cell lung cancer
Authors: Sos, Martin L.; Dietlein, Felix; Peifer, Martin; Schöttle, Jakob; Balke-Want, Hyatt; Müller, Christian; Koker, Mirjam; Richters, André; Heynck, Stefanie; Malchers, Florian; Heuckmann, Johannes M.; Seidel, Danila; Eyers, Patrick A.; Ullrich, Roland T.; Antonchick, Andrey P.; Vintonyak, Viktor V.; Schneider, Peter M.; Ninomiya, Takashi; Waldmann, Herbert; Büttner, Reinhard; Rauh, Daniel; Heukamp, Lukas C.; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012-10-16
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 109
Issue / Number: 42
Start Page: 17034
End Page: 17039
Sequence Number of Article: 1
Document Type: Article
ID: 628796.0
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
Authors: Peifer, Martin; Fernández-Cuesta, Lynnette; Sos, Martin L.; George, Julie; Seidel, Danila; Kasper, Lawryn H.; Plenker, Dennis; Leenders, Frauke; Sun, Ruping; Zander, Thomas; Menon, Roopika; Koker, Mirjam; Dahmen, Ilona; Müller, Christian; Di Cerbo, Vincenzo; Schildhaus, Hans-Ulrich; Altmüller, Janine; Baessmann, Ingelore; Becker, Christian; de Wilde, Bram; Vandesompele, Jo; Böhm, Diana; Ansén, Sascha; Gabler, Franziska; Wilkening, Ines; Heynck, Stefanie; Heuckmann, Johannes M.; Lu, Xin; Carter, Scott L.; Cibulskis, Kristian; Banerji, Shantanu; Getz, Gad; Park, Kwon-Sik; Rauh, Daniel; Grütter, Christian; Fischer, Matthias; Pasqualucci, Laura; Wright, Gavin; Wainer, Zoe; Russell, Prudence; Petersen, Iver; Chen, Yuan; Stoelben, Erich; Ludwig, Corinna; Schnabel, Philipp; Hoffmann, Hans; Muley, Thomas; Brockmann, Michael; Engel-Riedel, Walburga; Muscarella, Lucia A.; Fazio, Vito M.; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heideman, Danielle A. M.; Snijders, Peter J. F.; Capuzzo, Frederico; Ligorio, Claudia; Damiani, Stefania; Field, John; Solberg, Steinar; Brustugun, Odd Terje; Lund-Iversen, Marius; Sänger, Jörg; Clement, Joachim H.; Soltermann, Alex; Moch, Holger; Weder, Walter; Solomon, Benjamin; Soria, Jean-Charles; Valldire, Pierre; Besse, Benjamin; Brambilla, Elisabeth; Brambilla, Christian; Lantuejoul, Sylvie; Lorimier, Philippe; Schneider, Peter M.; Hallek, Michael; Pao, William; Meyerson, Matthew; Sage, Julien; Shendure, Jay; Schneider, Robert; Büttner, Reinhard; Wolf, Jürgen; Nürnberg, Peter; Perner, Sven; Heukamp, Lukas C.; Brindie, Paul K.; Haas, Stefan; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Nature Genetics
Volume: 44
Issue / Number: 10
Start Page: 1104-
End Page: 11xx
Document Type: Article
ID: 624882.0
A framework for identification of actionable cancer genome dependencies in small cell lung cancer
Authors: Sos, Martin L.; Dietlein, Felix; Peifer, Martin; Schöttle, Jakob; Balke-Want, Hyatt; Müller, Christian; Koker, Mirjam; Richters, André; Heynck, Stefanie; Malchers, Florian; Heuckmann, Johannes M.; Seidel, Danila; Eyers, Patrick A.; Ullrich, Roland T.; Antonchik, Andrey P.; Vintonyak, Viktor V.; Schneider, Peter M.; Ninomiya, Takashi; Waldmann, Herbert H.; Büttner, Reinhard; Rauh, Daniel; Heukamp, Lukas; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 109
Issue / Number: 42
Start Page: 17034
End Page: 17039
Document Type: Article
ID: 628397.0
Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino)isoquinoline-4-carbonitriles
as inhibitors of myosin light chain kinase and epidermal
growth factor receptor
Authors: Rode, Haridas B.; Sos, Martin L.; Grütter, Christian; Heynck, Stefanie; Simard, Jeffrey R.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2011-01
Title of Journal: Bioorganic & Medicinal Chemistry
Volume: 19
Issue / Number: 1
Start Page: 429
End Page: 439
Sequence Number of Article: 1
Document Type: Article
ID: 535425.0
Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino)isoquinoline-4-carbonitriles as inhibitors of myosin light chain kinase and epidermal growth factor receptor
Authors: Rode, Harras B.; Sos, Martin L.; Grütter, Christian; Heynck, Stefanie; Simard, Jeffrey R.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Bioorganic and Medicinal Chemistry
Volume: 19
Issue / Number: 1
Start Page: 429
End Page: 439
Document Type: Article
ID: 522174.0
ALK mutations conferring differential resistance to structurally diverse ALK inhibitors
Authors: Heuckmann, Johannes M.; Hölzel, Michael; Sos, Martin L.; Heynck, Stefanie; Balke-Want, Hyatt; Koker, Mirjam; Peifer, Martin; Weiss, Jonathan; Lovly, Christine M.; Grütter, Christian; Rauh, Daniel; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Clinical Cancer Research
Volume: 17
Issue / Number: 23
Start Page: 7394
End Page: 7401
Document Type: Article
ID: 575648.0
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
Authors: Hammerman, Peter S.; Sos, Martin L.; Ramos, Alex H.; Xu, Chunxiao; Dutt, Amit; Zhou, Wenjun; Brace, Lear E.; Woods, Brittany A.; Lin, Wenchu; Zhang, Jianming; Deng, Xianming; Lim, San Ming; Heynck, Stefanie; Peifer, Martin; Simard, Jeffrey R.; Lawrence, Michael S.; Onofrio, Robert C.; Salvesen, Helga B.; Seidel, Danila; Zander, Thomas; Heuckmann, Johannes M.; Soltermann, Alex; Moch, Holger; Koker, Mirjam; Leenders, Frauke; Gabler, Franziska; Querings, Silvia; Ansen, Sascha; Brambilla, Elisabeth; Brambilla, Christian; Lorimier, Philippe; Brustugun, Odd Terje; Helland, Aslaug; Petersen, Iver; Clement, Joachim H.; Groen, Harry; Timens, Wim; Sietsma, Hannie; Stoelben, Erich; Wolf, Jürgen; Beer, David G.; Tsao, Ming Sound; Hanna, Megan; Hatton, Charles; Eck, Michael J.; Janne, Pasi A.; Johnson, Bruce E.; Winckler, Wendy; Greulich, Heidi; Bass, Adam J.; Cho, Jeonghee; Rauh, Daniel; Gray, Nathanael S.; Wong, Kwok-Kin; Haura, Eric B.; Thomas, Roman K.; Meyerson, Matthew
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Cancer Discovery
Volume: 1
Issue / Number: 1
Start Page: 78
End Page: 89
Document Type: Article
ID: 589439.0
Synthesis and Biological Evaluation of 4-Anilinoquinolines as Potent Inibitors of Epidermal Growth Factor Receptor
Authors: Pawar, Vijaykumar G.; Sos, Martin L.; Rode, Haridas B.; Rabiller, Matthias; Heynck, Stefanie; Van Otterlo, Willem A. L.; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010-03-11
Title of Journal: Journal of Medicinal Chemistry
Volume: 53
Issue / Number: 7
Start Page: 2892
End Page: 2901
Sequence Number of Article: 1
Document Type: Article
ID: 475110.0
Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling
Authors: Peifer, Martin; Weiss, Jonathan; Sos, Martin L.; Koker, Mirjam; Heynck, Stefanie; Netzer, Christian; Fischer, Stefanie; Rode, Haridas; Rauh, Daniel; Rahnenführer, Jörg; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2010-01-27
Title of Journal: PLoS ONE
Volume: 5
Issue / Number: 1
Start Page: e8919
Sequence Number of Article: 1
Document Type: Article
ID: 455185.0
Entries: 1-10  
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