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Entries: 1-8  
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Overcoming Compound Fluorescence in the FLiK Screening Assay with Red-Shifted Fluorophores
Authors: Schneider, Ralf; Gohla, Anne; Simard, Jeffrey R.; Yadav, Dharmendra B.; Fang, Zhizhou; Van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-06-05
Title of Journal: Journal of the American Chemical Society
Volume: 135
Issue / Number: 22
Start Page: 8400
End Page: 8408
Sequence Number of Article: 1
Document Type: Article
ID: 668198.0
Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase
Authors: Getlik, Matthäus; Simard, Jeffrey R.; Termathe, Martin; Grütter, Christian; Rabiller, Matthias; Van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2012-07-02
Title of Journal: PLoS ONE
Volume: 7
Issue / Number: 7
Start Page: e39713-1
End Page: e39713-10
Sequence Number of Article: 1
Document Type: Article
ID: 611213.0
Design and Evaluation of Fragment-Like Estrogen Receptor Tetrahydroisoquinoline Ligands from a Scaffold- Detection Approach
Authors: Möcklinghoff, Sabine; Van Otterlo, Willem A. L.; Rose, Rolf; Fuchs, Sascha; Zimmermann, Tobias J.; Dominguez Seoane, Marta; Waldmann, Herbert; Ottmann, Christian; Brunsveld, Luc
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Journal of Medicinal Chemistry
Volume: 54
Issue / Number: 7
Start Page: 2005
End Page: 2011
Sequence Number of Article: 1
Document Type: Article
ID: 562907.0
Anticancer Properties of an Important Drug Lead Podophyllotoxin Can Be Efficiently Mimicked by Diverse Heterocyclic Scaffolds Accessible via One-Step Synthesis
Authors: Magedov, Igor V.; Frolova, Liliya; Manpadi, Madhuri; Bhoga, Uma devi; Tang, Hong; Evdokimov, Nikolai M.; George, Olivia; Georgiou, Kathy Hadje; Renner, Steffen; Getlik, Matthäus; Kinnibrugh, Tiffany L.; Fernandes, Manuel A.; Van Slambrouck, Severine; Steelant, Wim F. A.; Shuster, Charles B.; Rogelj, Snezna; Van Otterlo, Willem A. L.; Kornienko, Alexander
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Journal of Medicinal Chemistry
Volume: 54
Issue / Number: 12
Start Page: 4234
End Page: 4246
Sequence Number of Article: 1
Document Type: Article
ID: 570078.0
Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance
Authors: Klüter, Sabine; Simard, Jeffrey R.; Rode, Haridas B.; Grütter, Christian; Pawar, Vijaykumar; Raaijmakers, Hans C A.; Barf, Tjeerd A.; Rabiller, Matthias; van Otterlo, Willem A. L.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010-12-10
Title of Journal: ChemBioChem
Volume: 11
Issue / Number: 18
Start Page: 2557
End Page: 2566
Sequence Number of Article: 1
Document Type: Article
ID: 525509.0
Synthesis and Biological Evaluation of 4-Anilinoquinolines as Potent Inibitors of Epidermal Growth Factor Receptor
Authors: Pawar, Vijaykumar G.; Sos, Martin L.; Rode, Haridas B.; Rabiller, Matthias; Heynck, Stefanie; Van Otterlo, Willem A. L.; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010-03-11
Title of Journal: Journal of Medicinal Chemistry
Volume: 53
Issue / Number: 7
Start Page: 2892
End Page: 2901
Sequence Number of Article: 1
Document Type: Article
ID: 475110.0
Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor
Authors: Pawar, Vijakumar G.; Sos, Martin L.; Rode, Haridas B.; Rabiller, Matthias; Heynck, Stefanie; van Otterlo, Willem A. L.; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Journal of Medicinal Chemistry
Volume: 53
Issue / Number: 7
Start Page: 2892
End Page: 2901
Document Type: Article
ID: 472767.0
Bioactivity-guided mapping and navigation of chemical space
Authors: Renner, Steffen; Van Otterlo, Willem A. L.; Dominguez Seoane, Marta; Möcklinghoff, Sabine; Hofmann, Bettina; Wetzel, Stefan; Schuffenhauer, Ansgar; Ertl, Peter; Oprea, Tudor I.; Steinhilber, Dieter; Brunsveld, Luc; Rauh, Daniel; Waldmann, Herbert
Date of Publication (YYYY-MM-DD): 2009-06-28
Title of Journal: Nature Chemical Biology
Volume: 5
Issue / Number: 8
Start Page: 585
End Page: 592
Sequence Number of Article: 1
Document Type: Article
ID: 433910.0
Entries: 1-8  
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