Bonn, S., S. Herrero, C. B. Breitenlechner, A. Erlbruch, W. Lehmann, R. A. Engh, M. Gassel and D. Bossemeyer: Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. In: Journal of Biological Chemistry 281, 34, 24818-24830 (2006).
Breitenlechner, C. B., N. A. Kairies, K. Honold, S. Scheiblich, H. Koll, E. Greiter, S. Koch, W. Schafer, R. Huber and R. A. Engh: Crystal structures of active Src kinase domain complexes. In: Journal of Molecular Biology 353, 2, 222-231 (2005).
Breitenlechner, C. B., W. G. Friebe, E. Brunet, W. Guido, M. Graul, U. Thomas, K. P. Kunkele, W. Schafer, M. Gassel, D. Bosseineyer, R. Huber, R. A. Engh and B. Masjost: Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase a and mutants. In: Journal of Medicinal Chemistry 48, 1, 163-170 (2005).
Gassel, M., C. B. Breitenlechner, N. Konig, R. Huber, R. A. Engh and D. Bossemeyer: The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. In: Journal of Biological Chemistry 279, 22, 23679-23690 (2004).
Breitenlechner, C. B., T. Wegge, L. Berillon, K. Graul, M. Marzenell, W. G. Friebe, U. Thomas, R. Schumacher, R. Huber, R. A. Engh and B. Masjost: Structure-based optimization of novel azepane derivatives as PKB inhibitors. In: Journal of Medicinal Chemistry 47, 6, 1375-1390 (2004).
Bossemeyer, D., M. Gassel, C. B. Breitenlechner, S. H. de Vega and R. A. Engh: Insights into AGC-kinase inhibitor binding from studies with PKA.. In: Abstracts of Papers of the American Chemical Society 226, U461-U461 (2003).
Gassel, M., C. B. Breitenlechner, P. Ruger, U. Jucknischke, T. Schneider, R. Huber, D. Bossemeyer and R. A. Engh: Mutants of protein kinase a that mimic the ATP-binding site of protein kinase B (AKT). In: Journal of Molecular Biology 329, 5, 1021-1034 (2003).
Gassel, M., C. B. Breitenlechner, S. H. De Vega, R. A. Engh and D. Bossemeyer: Structural insights into AGC-kinase inhibitor binding from studies with the workhorse PKA. In: Cellular & Molecular Biology Letters 8, 2A, 508-509 (2003).
Ga├čel, M., C. B. Breitenlechner, R. A. Engh and D. Bossemeyer: Crystal structure of an altered catalytic subunit of cAMP-dependent protein kinase in complex with the Pkc-kinase inhibitor Bisindolyl-Maleimide 2 in two different conformations - implications for selectivity. In: Cellular and Molecular Biology Letters 8, 582-582 (2003).
Seifert, M. H. J., C. B. Breitenlechner, D. Bossemeyer, R. Huber, T. A. Holak and R. A. Engh: Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using P-31 NMR Spectroscopy. In: Biochemistry 41, 19, 5968-5977 (2002).
http://edoc.mpg.de
The Max Planck Society does not take any responsibility for the content of this export.