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Amplification of chromosomal segment 4q12 in non-small cell lung cancer
Authors: Ramos, Alex H.; Dutt, Amit; Mermel, Craig; Perner, Sven; Cho, Jeonghee; Lafargue, Christopher; Johnson, Laura A.; Stiedl, Ann-Cathrin; Tanaka, Kumiko E.; Bass, Adam J.; Barretina, Jordi; Weir, Barbara A.; Beroukhim, Rameen; Thomas, Roman K.; Minna, John D.; Chirieac, Lucian R.; Lindeman, Neal I.; Giordano, Thomas; Beer, David G.; Wagner, Patrick; Wistuba, Ignacio I.; Rubin, Mark A.; Meyerson, Matthew
Date of Publication (YYYY-MM-DD): 2009-11-01
Title of Journal: Cancer Biology and Therapy
Volume: 8
Issue / Number: 21
Start Page: 2042
End Page: 2050
Document Type: Article
ID: 441565.0


Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance
Authors: Shimamura, Takeshi; Li, Danan; Ji, Hongbin; Haringsma, Henry J.; Liniker, Elizabeth; Borgman, Christa L.; Lowell, April M.; Minami, Yuko; McNamara, Kate; Perera, Samanthi A.; Zaghlul, Sara; Thomas, Roman K.; Greulich, Heidi; Kobayashi, Susumu; Chirieac, Lucian R.; Padera, Robert F.; Kubo, Shigeto; Takahashi, Masaya; Tenen, Daniel G.; Meyerson, Matthew; Wong, Kwok-Kin; Shapiro, Geoffrey I.
Date of Publication (YYYY-MM-DD): 2008-07
Title of Journal: Cancer Research
Volume: 68
Issue / Number: 14
Start Page: 5827
End Page: 5838
Document Type: Article
ID: 380156.0


Characterizing the cancer genome in lung adenocarcinoma
Authors: Weir, Barbara A.; Woo, Michele S.; Getz, Gad; Perner, Sven; Ding, Li; Beroukhim, Rameen; Lin, William M.; Province, Michael A.; Kraja, Aldi; Johnson, Laura A.; Shah, Kinjal; Sato, Mitsuo; Thomas, Roman K.; Barletta, Justine A.; Borecki, Ingrid B.; Broderick, Stephen; Chang, Andrew C.; Chiang, Derek Y.; Chirieac, Lucian R.; Cho, Jeonghee; Fujii, Yoshitaka; Gazdar, Adi F.; Giordano, Thomas; Greulich, Heidi; Hanna, Megan; Johnson, Bruce E.; Kris, Mark G.; Lash, Alex; Lin, Ling; Lindeman, Neal; Mardis, Elaine R.; McPherson, John D.; Minna, John D.; Morgan, Margaret B.; Nadel, Mark; Orringer, Mark B.; Osborne, John R.; Ozenberger, Brad; Ramos, Alex H.; Robinson, James; Roth, Jack A.; Rusch, Valerie; Sasaki, Hidefumi; Shepherd, Frances; Sougnez, Carrie; Spitz, Margaret R.; Tsao, Ming-Sounf; Twomey, David; Verhaak, Roel G. W.; Weinstock, George M.; Wheeler, David A.; Winckler, Wendy; Yoshizawa, Akihiko; Yu, Soyoung; Zakowski, Maureen F.; Zhang, Qunyuan; Beer, David G.; Wistuba, Ignacio I.; Watson, Mark A.; Garraway, Levi A.; Ladanyi, Marc; Travis, William D.; Pao, William; Rubin, Mark A.; Gabriel, Stacey B.; Gibbs, Richard A.; Varmus, Harold E.; Wilson, Richard K.; Lander, Eric S.; Meyerson, Matthew
Date of Publication (YYYY-MM-DD): 2007-12-06
Title of Journal: Nature
Volume: 450
Issue / Number: 7171
Start Page: 893
End Page: 898
Document Type: Article
ID: 380157.0


Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy
Authors: Li, Danan; Shimamura, Takeshi; Ji, Hong Bin; Chen, Liang; Haringsma, Henry J.; McNamara, Kate; Liang, Mei-Chih; Perera, Samanthi A.; Zaghlul, Sara; Borgman, Christa L.; Kubo, Shigeto; Takahashi, Masaya; Sun, Yan Ping; Chirieac, Lucian R.; Padera, Robert F.; Lindeman, Neal I.; Janni, Pase A.; Thomas, Roman K.; Meyerson, Matthew L.; Eck, Michael J.; Engelman, Jeffrey A.; Shapiro, Geoffrey I.; Wong, Kwok-Kin
Date of Publication (YYYY-MM-DD): 2007-07
Title of Journal: Cancer Cell
Volume: 12
Issue / Number: 1
Start Page: 81
End Page: 93
Document Type: Article
ID: 376512.0


Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models
Authors: Ji, Hongbin; Wang, Zhenxiong; Perera, Samanthi A.; Li, Danan; Liang, Mei-Chih; Zaghlul, Sara; McNamara, Kate; Chen, Liang; Albert, Mitchell; Sun, Yanping; Al-Hashem, Ruqayyah; Chirieac, Lucian R.; Padera, Robert; Bronson, Roderick T.; Thomas, Roman K.; Garraway, Levi A.; J√§nne, Pasi A.; Johnson, Bruce E.; Chin, Lynda; Wong, Kwok-Kin
Date of Publication (YYYY-MM-DD): 2007-05-15
Title of Journal: Cancer Research
Volume: 67
Issue / Number: 10
Start Page: 4933
End Page: 4939
Document Type: Article
ID: 380158.0