Koes, D., K. Khoury, Y. J. Huang, W. Wang, M. Bista, G. M. Popowicz, S. Wolf, T. A. Holak, A. Domling and C. J. Camacho: Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists. In: PLoS ONE 7, 3, [1]-[8], Seq. No.: e32839 (2012).
doi: 10.1371/journal.pone.0032839
Huang, Y. J., S. Wolf, D. Koes, G. M. Popowicz, C. J. Camacho, T. A. Holak and A. Domling: Exhaustive Fluorine Scanning toward Potent p53-Mdm2 Antagonists. In: ChemMedChem 7, 1, 49-52 (2012).
Khoury, K., G. M. Popowicz, T. A. Holak and A. Domling: The p53-MDM2/MDMX axis - A chemotype perspective. In: Medchemcomm 2, 4, 246-260 (2011).
Popowicz, G. M., A. Domling and T. A. Holak: The Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious. In: Angewandte Chemie-International Edition 50, 12, 2680-2688 (2011).
Huang, Y. J., S. Wolf, M. Bista, L. Meireles, C. Camacho, T. A. Holak and A. Domling: 1,4-Thienodiazepine-2,5-diones via MCR (I): Synthesis, Virtual Space and p53-Mdm2 Activity. In: Chemical Biology & Drug Design 76, 2, 116-129 (2010).
Popowicz, G. M., A. Czarna, S. Wolf, K. Wang, W. Wang, A. Domling and T. A. Holak: Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery. In: Cell Cycle 9, 6, 1104-1111 (2010).
Czarna, A., B. Beck, S. Srivastava, G. M. Popowicz, S. Wolf, Y. J. Huang, M. Bista, T. A. Holak and A. Domling: Robust Generation of Lead Compounds for Protein-Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists. In: Angewandte Chemie-International Edition 49, 31, 5352-5356 (2010).
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