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Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling(RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG),and Leukemia-associated RhoGEF (LARG)
Authors: Jaiswal, Mamta; Gremer, Lothar; Dvorsky, Radovan; Haeusler, Lars Christian; Cirstea, Ion C.; Uhlenbrock, Katharina; Ahmadian, Mohammad Reza
Date of Publication (YYYY-MM-DD): 2011-05-20
Title of Journal: Journal of Biological Chemistry
Volume: 286
Issue / Number: 20
Start Page: 18202
End Page: 18212
Sequence Number of Article: 1
Document Type: Article
ID: 564518.0


Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders
Authors: Gremer, Lothar; Merbitz-Zahradnik, Torsten; Dvorsky, Radovan; Cirstea, Ion C.; Kratz, Christian Peter; Zenker, Martin; Wittinghofer, Alfred; Ahmadian, Mohammad Reza
Date of Publication (YYYY-MM-DD): 2010-10-14
Title of Journal: Human Mutation
Volume: 32
Issue / Number: 1
Start Page: 33
End Page: 43
Sequence Number of Article: 1
Document Type: Article
ID: 532656.0


Monoclonal antibody MN423 as a stable mold facilitates structure determination of disordered tau protein
Authors: Skrabana, Rostislav; Dvorsky, Radovan; Sevcik, Jozef; Novak, Michal
Date of Publication (YYYY-MM-DD): 2010-06
Title of Journal: Journal of Structural Biology
Volume: 171
Issue / Number: 1
Start Page: 74
End Page: 81
Sequence Number of Article: 1
Document Type: Article
ID: 478493.0


A restricted spectrum of NRAS mutations causes Noonan syndrome
Authors: Cirstea, Ion C.; Kutsche, Kerstin; Dvorsky, Radovan; Gremer, Lothar; Carta, Claudio; Horn, Denise; Roberts, Amy E.; Lepri, Francesca; Merbitz-Zahradnik, Torsten; König, Rainer; Kratz, Christian P.; Pantaleoni, Francesca; Dentici, Maria L.; Joshi, Victoria A.; Kucherlapati, Raju S.; Mazzanti, Laura; Mundlos, Stefan; Patton, Michael A.; Silengo, Margherita Cirillo; Rossi, Cesare; Zampino, Giuseppe; Digilio, Cristina; Stuppia, Liborio; Seemanova, Eva; Pennacchio, Len A.; Gelb, Bruce D.; Dallapiccola, Bruno; Wittinghofer, Alfred; Ahmadian, Mohammad R.; Tartaglia, Marco; Zenker, Martin
Date of Publication (YYYY-MM-DD): 2010-01
Title of Journal: Nature Genetics
Volume: 42
Issue / Number: 1
Start Page: 27
End Page: 29
Sequence Number of Article: 1
Document Type: Article
ID: 442399.0


Structure of RNase Sa2 complexes with mononucleotides - new aspects of catalytic reaction and substrate recognition
Authors: Bauerová-Hlinková, Vladena; Dvorský, Radovan; Perecko, Dusan; Povazanec, Frantisek; Sevcik, Jozef
Date of Publication (YYYY-MM-DD): 2009-06-25
Title of Journal: FEBS Journal
Volume: 276
Issue / Number: 15
Start Page: 4156
End Page: 4168
Sequence Number of Article: 1
Document Type: Article
ID: 433841.0


Mapping the Isoprenoid Binding Pocket of PDEδ by a Semisynthetic, Photoactivatable N-Ras Lipoprotein
Authors: Alexander, Michael; Gerauer, Marc; Pechlivanis, Markos; Popkirova, Boriana; Dvorsky, Radovan; Brunsveld, Luc; Waldmann, Herbert; Kuhlmann, Jürgen
Date of Publication (YYYY-MM-DD): 2009-01-05
Title of Journal: ChemBioChem
Volume: 10
Issue / Number: 1
Start Page: 98
End Page: 108
Sequence Number of Article: 1
Document Type: Article
ID: 397222.0


A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family
Authors: Eberth, Alexander; Lundmark, Richard; Gremer, Lothar; Dvorsky, Radovan; Koessmeier, Katja T.; McMahon, Harvey T.; Ahmadian, Mohammad Reza
Date of Publication (YYYY-MM-DD): 2009
Title of Journal: Biochemical Journal
Volume: 417
Issue / Number: 1
Start Page: 371
End Page: 377
Sequence Number of Article: 1
Document Type: Article
ID: 411644.0


X-ray structure of the PHF core C-terminus: Insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease
Authors: Sevcik, Jozef; Skrabana, Rostislav; Dvorsky, Radovan; Csokova, Natalia; Iqbal, Khalid; Novak, Michal
Date of Publication (YYYY-MM-DD): 2007-12-22
Title of Journal: FEBS Letters
Volume: 581
Issue / Number: 30
Start Page: 5872
End Page: 5878
Sequence Number of Article: 1
Document Type: Article
ID: 353830.0


A Novel Photoreaction Mechanism for the Circadian Blue Light Photoreceptor Drosophila Cryptochrome
Authors: Berndt, Alex; Kottke, Tilman; Breitkreuz, Helena; Dvorsky, Radovan; Hennig, Sven; Alexander, Michael; Wolf, Eva
Date of Publication (YYYY-MM-DD): 2007-04-27
Title of Journal: Journal of Biological Chemistry
Volume: 282
Issue / Number: 17
Start Page: 13011
End Page: 13021
Sequence Number of Article: 1
Document Type: Article
ID: 317035.0


Myopathy caused by HRAS germline mutations: implications for disturbed myogenic differentiation in the presence of constitutive HRas activation
Authors: Van der Burgt, Ineke; Kupsky, William; Stassou, Stephani; Nadroo, Ali; Barroso, Cândida; Diem, Angelika; Kratz, Christian P.; Dvorsky, Radovan; Ahmadian, Mohammad Reza; Zenker, Martin
Date of Publication (YYYY-MM-DD): 2007-04-05
Title of Journal: Journal of Medical Genetics
Volume: 44
Issue / Number: 7
Start Page: 459
End Page: 462
Sequence Number of Article: 1
Document Type: Article
ID: 319951.0