Koes, D., K. Khoury, Y. J. Huang, W. Wang, M. Bista, G. M. Popowicz, S. Wolf, T. A. Holak, A. Domling and C. J. Camacho: Enabling Large-Scale Design, Synthesis and Validation of Small Molecule Protein-Protein Antagonists. In: PLoS ONE 7, 3, [1]-[8], Seq. No.: e32839 (2012).
doi: 10.1371/journal.pone.0032839
Baek, S., P. S. Kutchukian, G. L. Verdine, R. Huber, T. A. Holak, K. W. Lee and G. M. Popowicz: Structure of the Stapled p53 Peptide Bound to Mdm2. In: Journal of the American Chemical Society 134, 1, 103-106 (2012).
Huang, Y. J., S. Wolf, D. Koes, G. M. Popowicz, C. J. Camacho, T. A. Holak and A. Domling: Exhaustive Fluorine Scanning toward Potent p53-Mdm2 Antagonists. In: ChemMedChem 7, 1, 49-52 (2012).
Sitar, T., J. Gallinger, A. M. Ducka, T. P. Ikonen, M. Wohlhoefler, K. M. Schmoller, A. R. Bausch, P. Joel, K. M. Trybus, A. A. Noegel, M. Schleicher, R. Huber and T. A. Holak: Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly. In: Proceedings of the National Academy of Sciences of the United States of America 108, 49, 19575-19580 (2011).
Graeber, M., W. Janczyk, B. Sperl, N. Elumalai, C. Kozany, F. Hausch, T. A. Holak and T. Berg: Selective Targeting of Disease-Relevant Protein Binding Domains by O-Phosphorylated Natural Product Derivatives. In: ACS Chemical Biology 6, 10, 1008-1014 (2011).
Gräber, M., W. Janczyk, B. Sperl, N. Elumalai, C. Kozany, F. Hausch, T. A. Holak and T. Berg: Selective Targeting of Disease-Relevant Protein Binding Domains by O-Phosphorylated Natural Product Derivatives. In: ACS Chemical Biology 6, 10, 1008-1014 (2011).
Orth, M., B. Mayer, K. Rehm, U. Rothweiler, D. Heidmann, T. A. Holak and O. Stemmann: Shugoshin is a Mad1/Cdc20-like interactor of Mad2. In: EMBO Journal 30, 14, 2868-2880 (2011).
Mishra, S. K., T. Ammon, G. M. Popowicz, M. Krajewski, R. J. Nagel, M. Ares, T. A. Holak and S. Jentsch: Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. In: Nature 474, 7350, 173-178 (2011).
Khoury, K., G. M. Popowicz, T. A. Holak and A. Domling: The p53-MDM2/MDMX axis - A chemotype perspective. In: Medchemcomm 2, 4, 246-260 (2011).
Popowicz, G. M., A. Domling and T. A. Holak: The Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious. In: Angewandte Chemie-International Edition 50, 12, 2680-2688 (2011).
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