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Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data
Authors: Fernandez-Cuesta, Lynnette; Sun, Ruping; Menon, Roopika; George, Julie; Lorenz, Susanne; Meza-Zepeda, Leonardo A.; Peifer, Martin; Plenker, Dennis; Heuckmann, Johannes M.; Leenders, Frauke; Zander, Thomas; Dahmen, Ilona; Koker, Mirjam; Schöttle, Jakob; Ullrich, Roland T.; Altmüller, Janine; Becker, Christian; Nürnberg, Peter; Seidel, Henrik; Böhm, Diana; Göke, Friederike; Ansen, Sascha; Russell, Prudence A.; Wright, Gavin M.; Wainer, Zoe; Solomon, Benjamin; Petersen, Iver; Clement, Joachim H.; Sänger, Jörg; Brustugun, Odd Terje; Helland, Aslaug; Solberg, Steinar; Lund-Iversen, Marius; Büttner, Reinhard; Wolf, Jürgen; Brambilla, Elisabeth; Vingron, Martin; Perner, Sven; Haas, Stefan A.; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2015
Title of Journal: Genome Biology
Volume: 16
Sequence Number of Article: 7
Document Type: Article
ID: 708977.0


Cell-autonomous and non-cell-autonomous mechanisms of transformation by amplified FGFR1 in lung cancer
Authors: Malchers, Florian; Dietlein, Felix; Schöttle, Jakob; Lu, Xin; Nogova, Lucia; Albus, Kerstin; Fernandez-Cuesta, Lynnette; Heuckmann, Johannes M.; Gautschi, Oliver; Diebold, Joachim; Plenker, Dennis; Gardizi, Masyar; Er, Matthias Scheffl; Bos, Marc; Seidel, Danila; Leenders, Frauke; Richters, André; Peifer, Martin; Florin, Alexandra; Mainkar, Prathama S.; Karre, Nagaraju; Chandrasekhar, Srivari; George, Julie; Silling, Steffi; Rauh, Daniel; Zander, Thomas; Ullrich, Roland T.; Reinhardt, H. Christian; Ringeisen, Francois; Buettner, Reinhard; Heukamp, Lukas C.; Wolf, Jürgen; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2014
Title of Journal: Cancer Discovery
Volume: 4
Issue / Number: 2
Start Page: 246
End Page: 257
Document Type: Article
ID: 695175.0


CD74-NRG1 fusions in lung adenocarcinoma
Authors: Fernandez-Cuesta, Lynette; Plenker, Dennis; Osada, Hirotaka; Sun, Ruping; Menon, Roopika; Leenders, Frauke; Ortiz-Cuaran, Sandra; Peifer, Martin; Bos, Marc; Daßler, Juliane; Malchers, Florian; Schöttle, Jakob; Vogel, Wenzel; Dahmen, Ilona; Koker, Mirjam; Ullrich, Roland T.; Wright, Gavin M.; Russell, Prudence A.; Wainer, Zoe; Solomon, Ben; Brambilla, Elisabeth; Nagy-Mignotte, Helene; Moro-Sibilot, Denis; Brambilla, Christian G.; Lantuejoul, Sylvie; Altmüller, Janine; Becker, Christian; Nürnberg, Peter; Heuckmann, Johannes M.; Stoelben, Erich; Petersen, Iver; Clement, Joachim H.; Sänger, Jörg; Muscarella, Lucia A.; la Torre, Annamaria; Fazio, Vito M.; Lahortiga, Idoya; Perera, Timothy; Ogata, Souichi; Parade, Marc; Brehmer, Dirk; Vingrom, Martin; Heukamp, Lukas C.; Buettner, Reinhard; Zander, Thomas; Wolf, Johanna; Perner, Sven; Ansen, Sascha; Haas, Stefan A.; Yatabe, Yasushi; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2014
Title of Journal: Cancer Discovery
Volume: 4
Issue / Number: 4
Start Page: 415
End Page: 422
Document Type: Article
ID: 695280.0


CD74-NRG1 fusions in lung adenocarcinoma
Authors: Fernandez-Cuesta, Lynette; Plenker, Dennis; Osada, Hirotaka; Sun, Ruping; Menon, Roopika; Leenders, Frauke; Ortiz-Cuaran, Sandra; Peifer, Martin; Bos, Marc; Daßler, Juliane; Malchers, Florian; Schöttle, Jakob; Vogel, Wenzel; Dahmen, Ilona; Koker, Mirjam; Ullrich, Roland T.; Wright, Gavin M.; Russell, Prudence A.; Wainer, Zoe; Solomon, Ben; Brambilla, Elisabeth; Nagy-Mignotte, Helene; Moro-Sibilot, Denis; Brambilla, Christian G.; Lantuejoul, Sylvie; Altmüller, Janine; Becker, Christian; Nürnberg, Peter; Heuckmann, Johannes M.; Stoelben, Erich; Petersen, Iver; Clement, Joachim H.; Sänger, Jörg; Muscarella, Lucia A.; la Torre, Annamaria; Fazio, Vito M.; Lahortiga, Idoya; Perera, Timothy; Ogata, Souichi; Parade, Marc; Brehmer, Dirk; Vingrom, Martin; Heukamp, Lukas C.; Buettner, Reinhard; Zander, Thomas; Wolf, Johanna; Perner, Sven; Ansen, Sascha; Haas, Stefan A.; Yatabe, Yasushi; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2014
Title of Journal: Cancer Discovery
Volume: 4
Issue / Number: 4
Start Page: 415
End Page: 422
Document Type: Article
ID: 695283.0


Targeting Gain of Function and Resistance Mutations in Abl and KIT by Hybrid Compound Design
Authors: Richters, André; Ketzer, Julia; Getlik, Matthäus; Grütter, Christian; Schneider, Ralf; Heuckmann, Johannes M.; Heynck, Stefanie; Sos, Martin L.; Gupta, Anu; Unger, Anke; Schultz-Fademrecht, Carsten; Thomas, Roman K.; Bauer, Sebastian; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2013-07-25
Title of Journal: Journal of Medicinal Chemistry
Volume: 56
Issue / Number: 14
Start Page: 5757
End Page: 5772
Sequence Number of Article: 1
Document Type: Article
ID: 669113.0


Tumor vegf:vegfr2 autocrine feed-forward loop triggers angiogenesis in lung cancer
Authors: Chatterjee, Sampurna; Heukamp, Lukas C.; Siobal, Maike; Schöttle, Jakob; Wieczorek, Caroline; Peifer, Martin; Frasca, Davide; Koker, Mirjam; König, Katharina; Meder, Lydia; Rauh, Daniel; Buettner, Reinhard; Wolf, Johanna; Brekken, Rolf A.; Neumaier, Bernd; Christofori, Gerhard; Thomas, Roman K.; Ullrich, Roland T.
Date of Publication (YYYY-MM-DD): 2013
Title of Journal: Journal of Clinical Investigation
Volume: 123
Issue / Number: 4
Start Page: 1732
End Page: 1740
Document Type: Article
ID: 655891.0


A framework for identification of actionable cancer genome dependencies in small cell lung cancer
Authors: Sos, Martin L.; Dietlein, Felix; Peifer, Martin; Schöttle, Jakob; Balke-Want, Hyatt; Müller, Christian; Koker, Mirjam; Richters, André; Heynck, Stefanie; Malchers, Florian; Heuckmann, Johannes M.; Seidel, Danila; Eyers, Patrick A.; Ullrich, Roland T.; Antonchick, Andrey P.; Vintonyak, Viktor V.; Schneider, Peter M.; Ninomiya, Takashi; Waldmann, Herbert; Büttner, Reinhard; Rauh, Daniel; Heukamp, Lukas C.; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012-10-16
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 109
Issue / Number: 42
Start Page: 17034
End Page: 17039
Sequence Number of Article: 1
Document Type: Article
ID: 628796.0


Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm
Authors: Chmielecki, Juliann; Peifer, Martin; Viale, Agnes; Hutchinson, Katherine; Giltnane, Jennifer; Socci, Nicholas D.; Dean, Rebecca S.; Yenamandra, Ashwini; Jagasia, Madan; Kim, Annette S.; Davé, Utpal P.; Thomas, Roman K.; Pao, William
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Genes Chromosomes and Cancer
Volume: 51
Issue / Number: 1
Start Page: 54
End Page: 65
Document Type: Article
ID: 573577.0


Systematic Screen for Tyrosine Kinase Rearrangements Identifies a Novel C6orf204-PDGFRB Fusion in a Patient with Recurrent T-ALL and an Associated Myeloproliferative Neoplasm
Authors: Chmielecki, Juliann; Peifer, Martin; Viale, Agnes; Hutchinson, Katherine; Giltnane, Jennifer; Socci, Nicholas D.; Hollis, Clayton J.; Dean, Rebecca S.; Yenamandra, Ashwini; Jagasia, Madan; Kim, Annette S.; Davé, Utpal P.; Thomas, Roman K.; Pao, William
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Genes, Chromosomes & Cancer
Volume: 51
Issue / Number: 1
Start Page: 54
End Page: 65
Sequence Number of Article: 1
Document Type: Article
ID: 576276.0


Genetic insight and therapeutic targets in squamous-cell lung cancer
Authors: Sos, Martin L.; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2012
Title of Journal: Oncogene
Volume: 31
Issue / Number: 46
Start Page: 4811
End Page: 4814
Document Type: Article
ID: 588143.0