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ALK mutations conferring differential resistance to structurally diverse ALK inhibitors
Authors: Heuckmann, Johannes M.; Hölzel, Michael; Sos, Martin L.; Heynck, Stefanie; Balke-Want, Hyatt; Koker, Mirjam; Peifer, Martin; Weiss, Jonathan; Lovly, Christine M.; Grütter, Christian; Rauh, Daniel; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Clinical Cancer Research
Volume: 17
Issue / Number: 23
Start Page: 7394
End Page: 7401
Document Type: Article
ID: 575648.0


Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling
Authors: Peifer, Martin; Weiss, Jonathan; Sos, Martin L.; Koker, Mirjam; Heynck, Stefanie; Netzer, Christian; Fischer, Stefanie; Rode, Haridas; Rauh, Daniel; Rahnenführer, Jörg; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2010-01-27
Title of Journal: PLoS ONE
Volume: 5
Issue / Number: 1
Start Page: e8919
Sequence Number of Article: 1
Document Type: Article
ID: 455185.0


Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling
Authors: Peifer, Martin; Weiss, Jonathan; Sos, Martin L.; Koker, Mirjam; Heynck, Stefanie; Netzer, Christian; Fischer, Stefanie; Rode, Haridas; Rauh, Daniel; Rahnenführer, Jörg; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: PLoS ONE
Volume: 5
Issue / Number: 1
Start Page: e8919
End Page: e8919
Document Type: Article
ID: 472768.0


Chemogenomic profiling provides insights into the limited activity of irreversible EGFR inhibitors in tumor cells expressing the T790M EGFR resistance mutation
Authors: Sos, Martin L.; Rode, Haridas B.; Heynck, Stefanie; Peifer, Martin; Fischer, Florian; Klüter, Sabine; Pawar, Vijakumar G.; Reuter, Cecile; Heuckmann, Johannes M.; Weiss, Jonathan; Ruddigkeit, Lars; Rabiller, Matthias; Koker, Mirjam; Simard, Jeffrey R.; Getlik, Matthäus; Yuza, Yuki; Chen, Tzu-Hsiu; Greulich, Heidi; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Cancer Research
Volume: 70
Issue / Number: 3
Start Page: 868
End Page: 874
Document Type: Article
ID: 472769.0


Chemogenomic Profiling Provides Insights into the Limited Activity of Irreversible EGFR Inhibitors in Tumor Cells Expressing the T790M EGFR Resistance Mutation
Authors: Sos, Martin L; Rode, Haridas B.; Heynck, Stefanie; Peifer, Martin; Fischer, Florian; Klüter, Sabine; Pawar, Vijaykumar G.; Reuter, Cecile; Heuckmann, Johannes M.; Weiss, Jonathan; Ruddigkeit, Lars; Rabiller, Matthias; Koker, Mirjam; Simard, Jeffrey R.; Getlik, Matthäus; Yuza, Yuki; Chen, Tzu-Hsiu; Greulich, Heidi; Thomas, Roman K.; Rauh, Daniel
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Cancer Research
Volume: 70
Issue / Number: 3
Start Page: 868
End Page: 874
Sequence Number of Article: 1
Document Type: Article
ID: 478045.0


Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
Authors: Weiss, Jonathan; Sos, Martin L.; Seidel, Danila; Peifer, Martin; Zander, Thomas; Heuckmann, Johannes M.; Ullrich, Roland T.; Menon, Roopika; Maier, Sebastian; Soltermann, Alex; Moch, Holger; Wagener, Patrick; Fischer, Florian; Heynck, Stefanie; Koker, Mirjam; Schöttle, Jakob; Leenders, Frauke; Gabler, Franziska; Dabow, Ines; Querings, Silvia; Heukamp, Lukas C.; Balke-Want, Hyatt; Ansén, Sascha; Rauh, Daniel; Baessmann, Ingelore; Altmüller, Janine; Wainer, Zoe; Conron, Matthew; Wright, Gavin; Russell, Prudence; Solomon, Ben; Brambilla, Elisabeth; Brambilla, Christian; Lorimier, Philippe; Sollberg, Steinar; Brustugun, Odd Terje; Engel-Riedel, Walburga; Ludwig, Corinna; Petersen, Iver; Sänger, Jörg; Clement, Joachim; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heidemann, Danielle; Cappuzzo, Frederico; Ligorio, Claudia; Damiani, Stefania; Hallek, Michael; Beroukhim, Rameen; Pao, William; Klebl, Bert; Baumann, Matthias; Buettner, Reinhard; Ernestus, Karen; Stoelben, Erich; Wolf, Jürgen; Nürnberg, Peter; Perner, Sven; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Science Translational Medicine
Volume: 2
Issue / Number: 62
Start Page: 62ra93
End Page: 62ra93
Document Type: Article
ID: 523811.0


Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
Authors: Weiss, Jonathan; Sos, Martin L.; Seidel, Danila; Peifer, Martin; Zander, Thomas; Heuckmann, Johannes M.; Ullrich, Roland T.; Menon, Roopika; Maier, Sebastian; Soltermann, Alex; Moch, Holger; Wagener, Patrick; Fischer, Florian; Heynck, Stefanie; Koker, Mirjam; Schöttle, Jakob; Leenders, Frauke; Gabler, Franziska; Dabow, Ines; Querings, Silvia; Heukamp, Lukas C.; Balke-Want, Hyatt; Ansén, Sascha; Rauh, Daniel; Baessmann, Ingelore; Altmüller, Janine; Wainer, Zoe; Conron, Matthew; Wright, Gavin; Russell, Prudence; Solomon, Ben; Brambilla, Elisabeth; Brambilla, Christian; Lorimier, Philippe; Sollberg, Steinar; Brustugun, Odd Terje; Engel-Riedel, Walburga; Ludwig, Corinna; Petersen, Iver; Sänger, Jörg; Clement, Joachim; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heidemann, Danielle; Cappuzzo, Frederico; Ligorio, Claudia; Damiani, Stefania; Hallek, Michael; Beroukhim, Rameen; Pao, William; Klebl, Bert; Baumann, Matthias; Buettner, Reinhard; Ernestus, Karen; Stoelben, Erich; Wolf, Jürgen; Nürnberg, Peter; Perner, Sven; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Science Translational Medicine
Volume: 2
Issue / Number: 62
Start Page: 62ra93
End Page: 62ra93
Document Type: Article
ID: 572952.0


Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stueckrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthaeus; Heukamp, Lukas C.; Ansen, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Start Page: 18351
End Page: 18356
Document Type: Article
ID: 436187.0


Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stückrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthäus; Heukamp, Lukas C.; Ansén, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Issue / Number: 43
Start Page: 18351
End Page: 18356
Sequence Number of Article: 1
Document Type: Article
ID: 439182.0


Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Authors: Sos, Martin L.; Fischer, Stefanie; Ullrich, Roland; Peifer, Martin; Heuckmann, Johannes M.; Koker, Mirjam; Heynck, Stefanie; Stueckrath, Isabel; Weiss, Jonathan; Fischer, Florian; Michel, Kathrin; Goel, Aviva; Regales, Lucia; Politi, Katerina A.; Perera, Samanthi; Getlik, Matthaeus; Heukamp, Lukas C.; Ansen, Sascha; Zander, Thomas; Beroukhim, Rameen; Kashkar, Hamid; Shokat, Kevan M.; Sellers, William R.; Rauh, Daniel; Orr, Christine; Hoeflich, Klaus P.; Friedman, Lori; Wong, Kwok-Kin; Pao, William; Thomas, Roman K.
Date of Publication (YYYY-MM-DD): 2009-10-27
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 106
Start Page: 18351
End Page: 18356
Document Type: Article
ID: 439375.0