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Impact of ribavirin on HCV replicon {RNA} decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir
Authors: Hofmann, Wolf Peter; Chung, Tje Lin; Osbahr, Carola; Susser, Simone; Karey, Ursel; Mihm, Ulrike; Welsch, Christoph; Lötsch, Jörn; Sarrazin, Christoph; Zeuzem, Stefan; Herrmann, Eva
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Antiviral Therapy
Volume: 16
Issue / Number: 5
Start Page: 695
End Page: 704
Document Type: Article
ID: 618846.0

Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
Authors: Shimakami, Tetsuro; Welsch, Christoph; Yamane, Daisuke; McGivern, David R.; Yi, MinKyung; Zeuzem, Stefan; Lemon, Stanley M.
Date of Publication (YYYY-MM-DD): 2011
Title of Journal: Gastroenterology
Volume: 140
Issue / Number: 2
Start Page: 667
End Page: 675
Document Type: Article
ID: 618848.0

Dimerization of the hepatitis C virus nonstructural protein {4B} depends on the integrity of an aminoterminal basic leucine zipper
Authors: Welker, Martin-Walter; Welsch, Christoph; Meyer, Aline; Antes, Iris; Albrecht, Mario; Forestier, Nicole; Kronenberger, Bernd; Lengauer, Thomas; Piiper, Albrecht; Zeuzem, Stefan; Sarrazin, Christoph
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Protein Science
Volume: 19
Issue / Number: 7
Start Page: 1327
End Page: 1336
Document Type: Article
ID: 536623.0

Effect of ribavirin on the frequency of RNAse {L} cleavage sites within the hepatitis {C} viral genome
Authors: Mihm, Ulrike; Hofmann, W.P.; Welsch, Christoph; Polta, A.; Lengauer, Thomas; Zeuzem, Stefan; Sarrazin, Christoph; Herrmann, E.
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Journal of Viral Hepatitis
Volume: 17
Issue / Number: 3
Start Page: 217
End Page: 221
Document Type: Article
ID: 536647.0

HLA class {I} allele associations with {HCV} genetic variants in patients with chronic {HCV} genotypes 1a or 1b infection
Authors: Lange, Christian Markus; Roomp, Kirsten; Dragan, Anette; Nattermann, Jacob; Michalk, Monika; Spengler, Ulrich; Weich, Viola; Lengauer, Thomas; Zeuzem, Stefan; Berg, Thoma; Sarrazin, Christoph
Date of Publication (YYYY-MM-DD): 2010
Title of Journal: Journal of Hepatology
Volume: 53
Issue / Number: 6
Start Page: 1022
End Page: 1028
Document Type: Article
ID: 536649.0

Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
Authors: Susser, Simone; Welsch, Christoph; Wang, Yalan; Zettler, Markus; Domingues, Francisco S.; Karey, Ursula; Hughes, Eric; Ralston, Robert; Tong, Xiao; Herrmann, Eva; Zeuzem, Stefan; Sarrazin, Christoph
Date of Publication (YYYY-MM-DD): 2009
Title of Journal: Hepatology
Volume: 50
Issue / Number: 6
Start Page: 1709
End Page: 1718
Document Type: Article
ID: 520908.0

Evaluation of the MLH1 I219V Alteration in DNA Mismatch Repair Activity and Ulcerative Colitis
Authors: Plotz, Guido; Raedle, Jochen; Spina, Anna; Welsch, Christoph; Stallmach, Andreas; Zeuzem, Stefan; Schmidt, Carsten
Date of Publication (YYYY-MM-DD): 2008
Title of Journal: Inflammatory Bowel Diseases
Volume: 14
Issue / Number: 5
Start Page: 605
End Page: 611
Document Type: Article
ID: 428192.0

Molecular basis of telaprevir resistance due to V36 and {T54} mutations in the {NS3-4A} protease of {HCV}
Authors: Welsch, Christoph; Domingues, Francisco S.; Susser, Simone; Antes, Iris; Hartmann, Christoph; Mayr, Gabriele; Schlicker, Andreas; Sarrazin, Christoph; Albrecht, Mario; Zeuzem, Stefan; Lengauer, Thomas
Date of Publication (YYYY-MM-DD): 2008
Title of Journal: Genome Biology
Volume: 9
Issue / Number: 1
Start Page: R16.1
End Page: 18
Document Type: Article
ID: 428255.0

Correlation of amino acid variations within nonstructural 4B protein with initial viral kinetics during interferon-alpha-based therapy in HCV-1b-infected patients
Authors: Welker, Martin W.; Hofmann, Wolf-Peter; Welsch, Christoph; von Wagner, Michael; Herrmann, Eva; Lengauer, Thomas; Zeuzem, Stefan; Sarrazin, Christoph
Date of Publication (YYYY-MM-DD): 2007
Title of Journal: Journal of Viral Hepatitis
Volume: 14
Start Page: 338
End Page: 349
Document Type: Article
ID: 356581.0

Identification and in silico characterization of a novel compound heterozygosty associated with hereditary aceruloplasminemia
Authors: Hofmann, Wolf Peter; Welsch, Christoph; Takahashi, Yoshitomo; Miyajima, Hiroaki; Mihm, Ulrike; Krick, Christoph; Zeuzem, Stefan; Sarrazin, Christoph
Date of Publication (YYYY-MM-DD): 2007
Title of Journal: Scandinavian Journal of Gastroenterology
Volume: 42
Issue / Number: 9
Start Page: 1088
End Page: 1094
Document Type: Article
ID: 356571.0