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Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations
Authors: Gilsbach, Bernd K.; Ho, Franz Y.; Vetter, Ingrid R.; Van Haastert, Peter J. M.; Wittinghofer, Alfred; Kortholt, Arjan
Date of Publication (YYYY-MM-DD): 2012-06-26
Title of Journal: Proceedings of the National Academy of Sciences of the United States of America
Volume: 109
Issue / Number: 26
Start Page: 10322
End Page: 10327
Sequence Number of Article: 1
Document Type: Article
ID: 611219.0


A Rap/Phosphatidylinositol 3-Kinase Pathway Controls Pseudopod Formation
Authors: Kortholt, Arjan; Bolourani, Parvin; Rehmann, Holger; Keizer-Gunnink, Ineke; Weeks, Gerald; Wittinghofer, Alfred; Van Haastert, Peter J. M.
Date of Publication (YYYY-MM-DD): 2010-03-15
Title of Journal: Molecular Biology of the Cell
Volume: 21
Issue / Number: 6
Start Page: 936
End Page: 945
Sequence Number of Article: 1
Document Type: Article
ID: 474569.0


Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase
Authors: Gotthardt, Katja; Weyand, Michael; Kortholt, Arjan; van Haastert, Peter J. M.; Wittinghofer, Alfred
Date of Publication (YYYY-MM-DD): 2008-07-24
Title of Journal: The EMBO Journal
Volume: 27
Issue / Number: 16
Start Page: 2239
End Page: 2249
Sequence Number of Article: 1
Document Type: Article
ID: 378738.0


Characterization of the GbpD-activated Rap1 Pathway Regulating Adhesion and Cell Polarity in Dictyostelium discoideum
Authors: Korholt, Arjan; Rehmann, Holger; Kae, Helmut; Bosgraaf, Leonard; Keizer-Gunnink, Ineke; Weeks, Gerald; Wittinghofer, Alfred; Van Haastert, Peter J. M.
Date of Publication (YYYY-MM-DD): 2006-08-18
Title of Journal: Journal of Biological Chemistry
Volume: 281
Issue / Number: 33
Start Page: 23367
End Page: 23376
Sequence Number of Article: 1
Document Type: Article
ID: 288372.0